Study Detail: AREDS 2

Age-related eye disease study 2

Trial Description

Summary

The objectives of this study are as follows:

• To evaluate the effect of high supplemental doses of lutein/zeaxanthin and omega 3 long chain polyunsaturated fatty acids (LCPFA) nutritional supplements on the progression to advanced age-related macular degeneration (AMD)
• To assess the effect of high supplemental doses of lutein/zeaxanthin and Omega 3 LCPFA nutritional supplements on moderate vision loss
• To evaluate the effect of eliminating beta-carotene and reducing zinc in the original AREDS nutritional supplement formulation

Basic Trial Information

Study Duration

5 years

Eligibility Criteria

Inclusion Criteria

• Large drusen in both eyes or large drusen in one eye and advanced age-related macular degeneration (neovascular AMD or geographic atrophy) in the other eye
• Several others

Exclusion Criteria

• Diabetic retinopathy (unless fewer than 10 microaneurysms and/or small hemorrhage)
• Several other retinal diseases
• Certain retinal or ocular surgeries, for example, laser trabeculectomy, cryosurgery (except for peripheral retinal hole), lamellar keratoplasty, pterygium surgery
• Cataract surgery less than 6 months before study entry
• Several others

Trial Contact Information