· Type 1 or Type 2 diabetic

· Patient ability to have fundus photos taken

· Presence of VMT associated with macular edema OR edema too diffuse to respond to focal or grid laser OR edema inadequately responsive to previous treatments & unlikely to benefit from further focal photocoagulation

· PPVX surgical treatment being performed as treatment for DME

· Please check with clinical coordinator for other inclusion criteria

· Macular edema due to other causes than diabetes

· Other ocular conditions present hat would not improve from resolution of macular edema or that might affect macular edema or alter visual acuity

· History of retinal macular photocoagulation, intravitreal corticosteroids or other treatment for DME within 3.5 months prior to enrollment

· History of peripheral scatter photocoagulation within 4 months prior to enrollment

· History of PPVX

· History of other major ocular surgery within 6 months prior to, or anticipated 6 months after enrollment

· History of YAG capsulotomy performed within 2 months prior to enrollment

· Please check with clinical coordinator for other exclusion criteria