|Condition or Disease||Intervention / Treatment||Phase||Sponsor||Status|
|Vitreomacular Traction||Intraocular Gas C3F8||2|| Jaeb Center for|
Eyes with idiopathic symptomatic Vitreomacular Traction (VMT) without a macular hole will be randomly assigned to 0.3mL intraocular gas (C3F8) injection or sham injection to determine if pneumatic vitreolysis (PVL) is effective in releasing VMT.
The objective of this trial is to obtain estimates of the proportion of eyes with foveal VMT release on OCT after PVL with gas injection versus observation (sham injection) in eyes with VMT without an associated Mac Hole.
Eyes with idiopathic symptomatic VMT will be randomly assigned to:
Perfluoropropane (C3F8) is an inert gas under pressure and is administered by injection into the vitreous cavity. It was approved by the FDA in February 1993 for the use of placing pressure on detached retina.
Study Eye Criteria: The participant must have at least one eye meeting all of the inclusion criteria and none of the exclusion criteria listed below. A participant can have only one study eye. If both eyes are eligible at the time of enrollment, the study eye will be selected by the investigator and participant before injection.
Inclusion - Study Eye:
Exclusion - Study Eye:
Inclusion Criteria - General:
To be eligible, the following inclusion criteria must be met: